Advanced Catalysis

Catalytic transformations that avoid stoichiometric reagents are key to making chemical reactions more selective and efficient in their use of raw materials and energy. For 20 years, ESIM Chemicals has been developing biocatalytic processes for chiral synthesis and racemate resolutions.

As a global-scale manufacturer we have overcome problems that are foreign to those who work only at laboratory scale. We share this unique knowledge as a member of one of Europe’s largest research networks. Other members bring expertise in areas such as microbial strain development and bioprocess technology. Together we pursue efficient, scalable routes to complex molecules that would have been difficult to access by chemical methods alone.

A strategic partnership with ESIM Chemicals will gain you access to:

  • Extensive experience in large-scale process implementations
  • Vast collections of biocatalysts and biocatalytic methods
  • Broad experience in bioprocess technologies
  • Deep knowledge of regulatory considerations
  • High-throughput screening capabilities
  • Expertise in large-scale chiral hydrogenations, carbonylations and C-C-couplings

Rather than pursue “me-too” solutions in secret, we’ve chosen to collaborate to rapidly advance one of the most challenging and rewarding areas of chemistry. It’s an approach where everybody wins – especially the customers of ESIM Chemicals. No company is better able to discern the catalytic processes that will prove to be overly complex from the ones that will reliably and efficiently accomplish your goals.

High Throughput Screening

The ESIM Chemicals Research & Development Center in Linz is equipped with semi-automatic high-throughput screening capabilities. The system can run up to four 50 ml reactors in parallel, has optional automated dosing via syringe pumps, and features a process control system to monitor and manage syntheses.

By making the investment to have this equipment in-house, ESIM Chemicals provides customers with greater process development efficiency, key safety data such as estimated heat generated by the reaction, and Design of Experiments (DoE) capabilities.